The safety of pediatric use of paracetamol (acetaminophen): a narrative review of direct and indirect evidence

Overall, the article compiles various lines of evidence probing the safety of acetaminophen for neurodevelopment. The article takes into account the view that the body's ability to tolerate acetaminophen is profoundly impaired by a condition called "oxidative stress." As the authors point out, a wide range of factors, including antibiotic use, infections, and exposure to pesticides, exposure to plastic-derived toxins, genetics, and even skipping meals, can unfortunately cause oxidative stress. The relation between acetaminophen, oxidative stress, and autism markers is discussed.